Jaguar Animal Health, Inc. (JAGX) gets new 24% activist owner; OpGen, Inc. (OPGN) gets new 6.9% passive owner

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Nantucket Investments Ltd has filed an SC 13D form with the Securities and Exchange Commission (SEC) disclosing ownership of 23,634,341 shares of Jaguar Animal Health, Inc. (NASDAQ:JAGX). This represents 24.9 percent ownership of the company. Previously, Nantucket Investments Ltd had reported owning 4,884,245 shares, indicating an increase of 383.89 percent. Jaguar Animal Health, Inc. has declared a standard industrial code (sic) of 2834 which is the “Pharmaceutical Preparations” industry.

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Armistice Capital, Llc has filed an SC 13G form with the Securities and Exchange Commission (SEC) disclosing ownership of 358,505 shares of OpGen, Inc. (NASDAQ:OPGN). This represents 6.9 percent ownership of the company. OpGen, Inc. has declared a standard industrial code (sic) of 8071 which is the "Medical Laboratories" industry.

When a person or group of persons acquires beneficial ownership of more than 5% of a company’s equity securities, they are required to file a Schedule 13D or 13G with the SEC. If these groups intend to influence management into changing the business strategy, they are considered "activist" investors. There is considerable academic research that suggest activist investors contribute to excess returns in equities in the subsequent twelve months after the event.

Investors that acquire 10% or more of a company's shares, or that gain a board seat, are considered insiders by the SEC and are subject to stricter insider trading filing requirements.

New Activist Investor Filings

Investors that acquire more than 5% of the shares of a company and intend to influence management are considered activist investors and must file a 13D.

MabVax Therapeutics Holdings, Inc. (MBVX) - Stetson John has filed a new SC 13D, reporting a 4.99% ownership stake in MabVax Therapeutics Holdings. This is a decrease of 11.52% from their previous filing.

Jaguar Animal Health, Inc. (JAGX) - Nantucket Investments Ltd has filed a new SC 13D, reporting a 24.90% ownership stake in Jaguar Animal Health. This is an increase of 25.13% from their previous filing.

Global Partner Acquisition Corp. (GPAC) - Coliseum Capital Management, LLC has filed a new SC 13D, reporting a 65.10% ownership stake in Global Partner Acquisition.

Marrone Bio Innovations, Inc. (MBII) - Ospraie Ag Science Llc has filed a new SC 13D, reporting a 46.20% ownership stake in Marrone Bio Innovations.

New Passive Investor Filings

Investors that acquire more than 5% of the shares of a company but have no intention of influencing management are considered passive investors and must file a 13G.

Equity Commonwealth (EQC) - Henderson Group Plc has filed a new SC 13G, reporting a 5.50% ownership stake in Equity Commonwealth.

Financial Engines, Inc. (FNGN) - Henderson Group Plc has filed a new SC 13G, reporting a 6.10% ownership stake in Financial Engines.

SEACOR Marine Holdings Inc. (SMHI) - Fabrikant Charles has filed a new SC 13G, reporting a 6.17% ownership stake in SEACOR Marine Holdings.

Global Blood Therapeutics, Inc. (GBT) - Henderson Group Plc has filed a new SC 13G, reporting a 6.90% ownership stake in Global Blood Therapeutics.

ICU Medical, Inc. (ICUI) - Henderson Group Plc has filed a new SC 13G, reporting a 7.40% ownership stake in ICU Medical.

Advanced Emissions Solutions, Inc. (ADES) - Apollo Management Holdings GP, LLC has filed a new SC 13G, reporting a 5.60% ownership stake in Advanced Emissions Solutions.

Sunesis Pharmaceuticals, Inc. (SNSS) - Eventide Asset Management, Llc has filed a new SC 13G, reporting a 6.60% ownership stake in Sunesis Pharmaceuticals.

Insmed, Inc. (INSM) - Henderson Group Plc has filed a new SC 13G, reporting a 7.80% ownership stake in Insmed.

Pandora Media, Inc. (P) - Ontario Teachers Pension Plan Board has filed a new SC 13G, reporting a 6.43% ownership stake in Pandora Media.

Carbylan Therapeutics, Inc. (CBYL) - Eventide Asset Management, Llc has filed a new SC 13G, reporting a 6.60% ownership stake in Carbylan Therapeutics.

Gartner, Inc. (IT) - Henderson Group Plc has filed a new SC 13G, reporting a 5.50% ownership stake in Gartner.

J. Jill, Inc. (JILL) - TowerBrook Investors, Ltd. has filed a new SC 13G, reporting a 58.90% ownership stake in J. Jill.

Milacron Holdings Corp. (MCRN) - Henderson Group Plc has filed a new SC 13G, reporting a 5.20% ownership stake in Milacron Holdings.

Neurocrine Biosciences, Inc. (NBIX) - Henderson Group Plc has filed a new SC 13G, reporting a 6.50% ownership stake in Neurocrine Biosciences.

LaSalle Hotel Properties (LHO) - Morgan Stanley has filed a new SC 13G, reporting a 6.40% ownership stake in LaSalle Hotel Properties. This is an increase of 30.61% from their previous filing.

OpGen, Inc. (OPGN) - Armistice Capital, Llc has filed a new SC 13G, reporting a 6.90% ownership stake in OpGen.

Kala Pharmaceuticals, Inc. (KALA) - Longitude Capital Partners II, LLC has filed a new SC 13G, reporting a 9.30% ownership stake in Kala Pharmaceuticals.

ASV Holdings Inc. (ASV) - Manitex International, Inc. has filed a new SC 13G, reporting a 21.20% ownership stake in ASV Holdings.

Amicus Therapeutics, Inc. (FOLD) - venBio Select Advisor LLC has filed a new SC 13G, reporting a 5.30% ownership stake in Amicus Therapeutics.

Restoration Robotics, Inc. (HAIR) - Clarus Lifesciences II, L.P. has filed a new SC 13G, reporting a 12.34% ownership stake in Restoration Robotics.

Cal-Maine Foods, Inc. (CALM) - Henderson Group Plc has filed a new SC 13G, reporting a 5.30% ownership stake in Cal-Maine Foods.

Sabre Corporation (SABR) - Burgundy Asset Management Ltd. has filed a new SC 13G, reporting a 5.09% ownership stake in Sabre.

Hess Midstream Partners LP (HESM) - Global Infrastructure Investors Ii, Llc has filed a new SC 13G, reporting a new ownership stake in Hess Midstream Partners.

Central European Media Enterprises Ltd. (CETV) - Henderson Group Plc has filed a new SC 13G, reporting a 5.20% ownership stake in Central European Media Enterprises.

Okta, Inc. (OKTA) - Khosla Ventures IV, L.P. has filed a new SC 13G, reporting a 7.50% ownership stake in Okta.

CSW Industrials, Inc. (CSWI) - Henderson Group Plc has filed a new SC 13G, reporting a 6.00% ownership stake in CSW Industrials.

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