Off to a strong start this week are today’s top midday gainers: Sarepta Therapeutics Inc (NASDAQ:SRPT), Advanced Micro Devices, Inc. (NYSE:AMD) and Sears Hometown and Outlet Stores Inc (NASDAQ:SHOS). On the losng end are Atlas Energy LP (NYSE:ATLS), Allied Nevada Gold Corp. (NYSEMKT:ANV) and International Tower Hill Mines Ltd (NYSEMKT:THM).

chart_1 (1) Sarepta

FDA Decision Spurs Sarepta Rally

Today’s top gainer is Sarepta Therapeutics Inc (NASDAQ:SRPT). The George Soros biopharmaceutical pick jumped a staggering +49.34% after the announcement that the FDA has accepted a new drug application for one of its most controversial products.

At a very distant second is Advanced Micro Devices, Inc. (NYSE:AMD), up +11.11%. The company reported late last week that its first-quarter loss had narrowed on stronger sales data. Tiger Global Management currently has a stake in AMD.

Edward Lampert’s Sears Hometown and Outlet Stores Inc (NASDAQ:SHOS) jumped +6.40% midday this Monday. Sears remains down -7.47% YTD.

Atlas Energy Takes a Dive

Today’s biggest loser midday is Atlas Energy LP (NYSE:ATLS), its price slipping -7.77%. ATLS shares surged +4.62% last week but have still declined -14.60% this year. Leon Cooperman has a stake in the firm.

Mining company Allied Nevada Gold Corp. (NYSEMKT:ANV) posted a -6.33% loss. The John Paulson gold explorer is being dragged down by investigations into its accounting practices.

Another Paulson pick, International Tower Hill Mines Ltd (NYSEMKT:THM), takes the third spot on today’s list of losers, its price falling -6.19%. Since last Monday, it has declined -19.25%. However, it’s up +55.59% for the year.